Scottish Trace Element & Micronutrient Reference Laboratory

Scotland's specialised laboratory for trace elements and vitamins in health and disease

2024

The effect of acute and chronic inflammatory response on plasma and erythrocyte selenium concentrations: Implications for assessing selenium nutritional status. Anthony Catchpole, Donogh Maguire, John M. Wadsworth, Donald C. McMillan, Owen Sheerins, Mark Blyth, Andrew Shaw, Bryn Jones, Colin Drury, Dinesh Talwar. Clin Nutr Open Science. 2024; 53: 25-34.


Plasma and red blood cell concentrations of zinc, copper, selenium and magnesium in the first week of paediatric critical illness. Veldscholte K, Al Fify M, Catchpole A, Talwar D, Wadsworth J, Vanhorebeek I, Casaer MP, Van den Berghe G, Joosten KFM, Gerasimidis K, Verbruggen SCAT. Clin Nutr. 2024 Feb;43(2):543-551.


The science of micronutrients in clinical practice - Report on the ESPEN symposium. Berger MM, Amrein K, Barazzoni R, Bindels L, Bretón I, Calder PC, Cappa S, Cuerda C, D'Amelio P, de Man A, Delzenne NM, Forbes A, Genton L, Gombart AF, Joly F, Laviano A, Matthys C, Phyo PP, Ravasco P, Serlie MJ, Shenkin A, Stoffel NU, Talwar D, van Zanten ARH.  Clin Nutr. 2024 Jan;43(1):268-283.

 

2023

The relationship between micronutrient status, frailty, systemic inflammation, and clinical outcomes in patients admitted to hospital with COVID-19. McGovern J, Wadsworth J, Catchpole A, Richards C, McMillan DC, Kelliher T, Goodall E, Murray E, Melaugh T, McPhillips S, Brice K, Barbour K, Robinson S, Moffitt P, Kemp O, Talwar D, Maguire D. J Transl Med. 2023 Apr 28;21(1):284.

Pitfalls in the interpretation of blood tests used to assess and monitor micronutrient nutrition status. Berger MM, Talwar D, Shenkin A. Nutr Clin Pract. 2023 Feb;38(1):56-69.

Total plasma magnesium, zinc, copper and selenium concentrations in obese patients before and after bariatric surgery. Stephen J. Hierons, Anthony Catchpole, Kazim Abbas, Wingzou Wong, Mathew S. Giles, Glenn V. Miller, Ramzi A. Ajjan & Alan J. Stewart. BioMetals 2023;36,241–253.


2022

Randomised trial of intravenous thiamine and/or magnesium sulphate administration on erythrocyte transketolase activity, lactate concentrations and alcohol withdrawal scores. Donogh Maguire, Alana Burns, Dinesh Talwar, Anthony Catchpole, Fiona Stefanowicz, David P. Ross, Peter Galloway, Alastair Ireland, Gordon Robson, Michael Adamson, Lesley Orr, Joanna-Lee Kerr, Xenofon Roussis, Eoghan Colgan, Ewan Forrest, David Young, Donald C. McMillan. Sci Rep. 2022; 12: 6941.

Development of age-dependent micronutrient centile charts and their utility in children with chronic gastrointestinal conditions at risk of deficiencies: A proof-of-concept study. Maha Al Fify, Ben Nichols, Lefkothea Arailoudi Alexiadou, Fiona Stefanowicz, Janis Armstrong, Richard K. Russell, Adrian Raudaschl, Naina Pinto, Andrew Duncan, Anthony Catchpole, Peter Galloway, Dinesh Talwar, Konstantinos Gerasimidis. Clin Nutr. 2022;41(4):931-936.


2021

The relation between acute changes in the systemic inflammatory response and circulating thiamine and magnesium concentrations after elective knee arthroplasty. Donogh Maguire, Anthony Catchpole, Owen Sheerins, Dinesh Talwar, Alana Burns, Mark Blyth, Andrew Shaw, Bryn Jones, Colin Drury, Johann Harten, Innes Smith, Donald C. McMillan. Sci Rep. 2021; 11: 11271.

The systemic inflammatory response and clinicopathological characteristics in patients admitted to hospital with COVID-19 infection: Comparison of 2 consecutive cohorts. Donogh Maguire, Conor Richards, Marylynne Woods, Ross Dolan, Jesse Wilson Veitch, Wei M. J. Sim, Olivia E. H. Kemmett, David C. Milton, Sophie L. W. Randall, Ly D. Bui, Nicola Goldmann, Amy Brown, Eilidh Gillen, Allan Cameron, Barry Laird, Dinesh Talwar, Ian M. Godber, John Wadsworth, Anthony Catchpole, Alan Davidson, Donald C. McMillan. PLoS One. 2021; 16(5): e0251924.

A prospective analysis of micronutrient status in quiescent inflammatory bowel disease. MacMaster MJ, Damianopoulou S, Thomson C, Talwar D, Stefanowicz F, Catchpole A, Gerasimidis K, Gaya DR. Clin Nutr. 2021; 40(1):327-331.

Micronutrient deficiencies in children with coeliac disease; a double-edged sword of both untreated disease and treatment with gluten-free diet. Lorcan McGrogan, Mary Mackinder, Fiona Stefanowicz, Maria Aroutiounova, Anthony Catchpole, John Wadsworth, Elaine Buchanan, Tracey Cardigan, Hazel Duncan, Richard Hansen, Richard K Russell, Christine A Edwards, Dinesh Talwar, Paraic McGrogan, Konstantinos Gerasimidis. Clin Nutr. 2021;40(5):2784-2790.


2020

The relationship between plasma albumin, alkaline phosphatase and pyridoxal phosphate concentrations in plasma and red cells: Implications for assessing vitamin B6 status. D Talwar, A Catchpole, JM Wadsworth, BJ Toole, DC McMillan. Clin Nutr. 2020;39(9):2824-2831.

Assessment and Interpretation of Vitamin and Trace Element Status in Sick Children: A Position Paper from the European Society for Paediatric Gastroenterology Hepatology, and Nutrition Committee on Nutrition. Konstantinos Gerasimidis, Jiri Bronsky, Anthony Catchpole et al. J Pediatr Gastroenterol Nutr. 2020;70(6):873-881.

Three‐year follow up of using combination therapy with fresh‐frozen plasma and iron chelation in a patient with acaeruloplasminemia. Andreas Tridimas, Godfrey T. Gillett, Sally Pollard, Nandini Sadasivam, Adrian Williams, Kirsty Mellor, Anthony Catchpole, Karolina M. Stepien. JIMD Rep. 2020;57(1):23-28.

Comparison of Thiamin Diphosphate High-Performance Liquid Chromatography and Erythrocyte Transketolase Assays for Evaluating Thiamin Status in Malaria Patients without Beriberi. Andrew J Taylor, Dinesh Talwar, Sue J Lee, Lorna Cox, Mayfong Mayxay, Paul N Newton. Am J Trop Med Hyg. 2020;103(6):2600-2604.

Prognostic factors in patients admitted to an urban teaching hospital with COVID-19 infection. Donogh Maguire, Marylynne Woods, Conor Richards, Ross Dolan, Jesse Wilson Veitch, Wei M. J. Sim, Olivia E. H. Kemmett, David C. Milton, Sophie L. W. Randall, Ly D. Bui, Nicola Goldmann, Allan Cameron, Barry Laird, Dinesh Talwar, Ian Godber, Alan Davidson and Donald C. McMillan. J Transl Med. 2020; 18: 354.

Atomic spectrometry update: review of advances in the analysis of clinical and biological materials, foods and beverages. Taylor A, Catchpole A, Day MP, Hill S, Martin N, Patriarca M. J. Anal. At. Spectrom., 2020,35, 426-454.

 

2019

Low serum magnesium and 1‐year mortality in alcohol withdrawal syndrome. D Maguire, DP Ross, D Talwar, E Forrest, H Naz Abbasi, JP Leach et al. Eur J Clin Invest. 2019;49 (9), e13152.

A prospective evaluation of thiamine and magnesium status in relation to clinicopathological characteristics and 1-year mortality in patients with alcohol withdrawal syndrome. D Maguire, D Talwar, A Burns, A Catchpole, F Stefanowicz, G Robson et al. Journal of translational medicine 2019; 17(1):384.

Regression correction equation to adjust serum iron and ferritin concentrations based on C-reactive protein and albumin in patients receiving primary and secondary care. ST McSorley, A Tham, I Jones, D Talwar, DC McMillan. The Journal of nutrition 2019; 149 (5), 877-88.

Relationship between nutritional status and the systemic inflammatory response: micronutrients. McMillan DC, Maguire D, Talwar D. Proc Nutr Soc. 2019 Feb;78(1):56-67.

PWE-036 A prospective audit of the 2017 espen guidelines on micronutrient testing in quiescent IBD patients. MacMaster M, Thomson C, Talwar D, Stefanowicz F, Gerasimidis K, Gaya D. Gut 2018;67:A85.

The relationship between the systemic inflammatory response and plasma and erythrocyte selenium in patients presenting for nutritional assessment. Catchpole A, Stefanowicz F, McMillan D, Talwar D. Clin Nut. 2018;37:S33.

 

2017

Interpreting iron studies. Kelly AU, McSorley ST, Patel P, Talwar D. BMJ. 2017 Jun 15;357:j2513. doi: 10.1136/bmj.j2513.

ANNALS EXPRESS: The Role of Calculated Non-Caeruloplasmin Bound Copper in Wilson's Disease. Duncan A, Yacoubian C, Beetham R, Catchpole A, Bullock D. Ann Clin Biochem. 2017;54(6):649-654.

 

2016

Balmforth C, van Bragt JJ, Ruijs T, Cameron JR, Kimmitt R, Moorhouse R, Czopek A, Hu MK, Gallacher PJ, Dear JW, Borooah S, MacIntyre IM, Pearson TM, Willox L, Talwar D, Tafflet M, Roubeix C, Sennlaub F, Chandran S, Dhillon B, Webb DJ, Dhaun N. Chorioretinal thinning in chronic kidney disease links to inflammation and endothelial dysfunction. JCI Insight. 2016; 1(20):e89173.

Quantitative data on the magnitude of the systemic inflammatory response and its relationship with serum measures of iron status. McSorley ST, Jones I, McMillan DC, Talwar D. Transl Res. 2016; 176:119-26. doi: 10.1016/j.trsl.2016.05.004.

Duncan A, Talwar D, Morrison I. The predictive value of low plasma copper and high plasma zinc in detecting zinc-induced copper deficiency. Ann Clin Biochem. 2015 Nov 19.

Duncan A, Yacoubian C, Watson N, Morrison I. The risk of copper deficiency in patients prescribed zinc supplements. J Clin Path. 2015;68:723-725.

Proctor MJ, McMillan DC, Horgan PG, Fletcher CD, Talwar D, Morrison DS. Systemic inflammation predicts all-cause mortality: a Glasgow inflammation outcome study.PLoS One. 2015 Mar 2;10(3):e0116206.

Conway FJ, Talwar D, McMillan DC. The relationship between acute changes in the systemic inflammatory response and plasma ascorbic acid, alpha-tocopherol and lipid peroxidation after elective hip arthroplasty. Clin Nutr. 2014 Jul 10.pii: S0261-5614(14)00180-0.

Stefanowicz F; Gashut RA; Talwar D; Duncan A; Beulshausen JF; McMillan DC; Kinsella J. Assessment of plasma and red cell trace element concentrations, disease severity, and outcome in patients with critical illness. J Crit Care. 29(2):214-8, 2014 Apr.

 

2015

Duncan A, Talwar D, Morrison I. The predictive value of low plasma copper and high plasma zinc in detecting zinc-induced copper deficiency. Ann Clin Biochem. 2015 Nov 19. pii: 0004563215620821.

Duncan A, Gallacher G, Willox L. The role of the clinical biochemist in detection of zinc-induced copper deficiency. Ann Clin Biochem. 2015; doi:10.1177/0004563215595429.

Duncan A, Yacoubian C, Watson N, Morrison I. The risk of copper deficiency in patients prescribed zinc supplements. J Clin Path. 2015;68:723-725.

Ghashut RA, McMillan DC, Kinsella J, Vasilaki AT, Talwar D, Duncan A. The effect of the systemic inflammatory response on plasma zinc and selenium adjusted for albumin. Clin Nutr. 2015 Feb 26.pii: S0261-5614(15)00053-9. doi: 10.1016/j.clnu.2015.02.010.

Proctor MJ, McMillan DC, Horgan PG, Fletcher CD, Talwar D, Morrison DS. Systemic inflammation predicts all-cause mortality: a Glasgow inflammation outcome study. PLoS One. 2015 Mar 2;10(3):e0116206. doi: 10.1371/journal.pone.0116206. eCollection 2015.

Duncan A, Taylor A, Leese E, Allen S, Morton J, McAdam J. Homicidal arsenic poisoning. Ann Clin Biochem. 2015;52:510-515.

 

2014

Stefanowicz F, Gashut RA, Talwar D, Duncan A, Beulshausen JF, McMillan DC, Kinsella J. Assessment of plasma and red cell trace element concentrations, disease severity, and outcome in patients with critical illness. J Crit Care. 2014;29:214-8.

Kilpatrick S1, Jacinto A, Foale RD, Tappin SW, Burton C, Frowde PE, Elwood CM, Powell R, Duncan A, Mellanby RJ, Gow AG. Whole blood manganese concentrations in dogs with primary hepatitis. J Small Anim Pract. 2014;55:241-6.

Conway FJ, Talwar D, McMillan DC. The relationship between acute changes in the systemic inflammatory response and plasma ascorbic acid, alpha-tocopherol and lipid peroxidation after elective hip arthroplasty. Clin Nutr. 2014 Jul 10.pii: S0261-5614(14)00180-0. doi: 10.1016/j.clnu.2014.07.004.

Ghashut RA, TalwarD, Kinsella J, Duncan A, McMillan DC.The effect of the systemic inflammatory response on plasma vitamin 25 (OH) D concentrations adjusted for albumin. PLoS One. 2014 Mar 25;9(3):e92614. doi: 10.1371/journal.pone.0092614.

 

2013

Stefanowicz FA, Talwar D, O'Reilly DS, Dickinson N, Atkinson J, Hursthouse AS, Rankin J, Duncan A. Erythrocyte selenium concentration as a marker of selenium status. Clin Nutr.2013;32(5):837-42.

Proctor MJ, Horgan PG, Talwar D, Fletcher CD, Morrison DS, McMillan DC. Optimization of the systemic inflammation-based Glasgow prognostic score: a Glasgow Inflammation Outcome Study. Cancer 2013;119(12):2325-32.

Gerasimidis K, Edwards C, Stefanowicz F, Galloway P, McGrogan P, Duncan A, Talwar D. Micronutrient status in children with IBD: true deficiencies or epiphenomenon of the systemic inflammatory response. J Pediatr Gastroent Nutr. 2013;56(6):e50-1.

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